Researchers home in on genes linked to age-related macular degeneration

Researchers home in on genes linked to age-related macular degeneration

"If we were conducting a criminal investigation, prior research would have localized different crime syndicates to 52 streets within 34 zip codes. These latest findings identify actual suspects -- direct targets that we can more closely investigate", said the study's lead investigator Anand Swaroop, Ph.D., chief of the Neurobiology-Neurodegeneration and Repair Laboratory at NEI, which is part of the National Institutes of Health. Previously, Swaroop and colleagues had compared populations of people with and without AMD and identified 34 small genomic regions -- called loci -- and 52 genetic variants within these loci that were significantly associated with AMD.

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